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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2003 1
2004 1
2006 1
2007 1
2008 1
2009 2
2011 1
2012 1
2014 1
2015 2
2016 2
2017 1
2018 1
2019 2
2020 5
2021 1
2023 1
2024 0

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24 results

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Page 1
CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands.
Korbecki J, Grochans S, Gutowska I, Barczak K, Baranowska-Bosiacka I. Korbecki J, et al. Int J Mol Sci. 2020 Oct 15;21(20):7619. doi: 10.3390/ijms21207619. Int J Mol Sci. 2020. PMID: 33076281 Free PMC article. Review.
In this review, we discuss human CC motif chemokine ligands: CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CCL28 (CC motif chemokine receptor CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 ligands). ...
In this review, we discuss human CC motif chemokine ligands: CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CC …
CCR6 supports migration and differentiation of a subset of DN1 early thymocyte progenitors but is not required for thymic nTreg development.
Bunting MD, Comerford I, Kara EE, Korner H, McColl SR. Bunting MD, et al. Immunol Cell Biol. 2014 Jul;92(6):489-98. doi: 10.1038/icb.2014.14. Epub 2014 Mar 18. Immunol Cell Biol. 2014. PMID: 24638065
In this study, we addressed this by analyzing expression of CCR6/CCL20 within the thymus and assessing their role in thymocyte development using Ccr6(-/-) mice. ...The data indicate that nTreg frequencies and localization are unperturbed by deletion of Ccr6. …
In this study, we addressed this by analyzing expression of CCR6/CCL20 within the thymus and assessing their role in thymocyte develo …
Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjogren's syndrome to facilitate their concerted migration.
Blokland SLM, Kislat A, Homey B, Smithson GM, Kruize AA, Radstake TRDJ, van Roon JAG. Blokland SLM, et al. Scand J Immunol. 2020 Mar;91(3):e12852. doi: 10.1111/sji.12852. Epub 2019 Dec 13. Scand J Immunol. 2020. PMID: 31733111 Free PMC article.
Frequencies of circulating CCR9 + and CCR9- Th cells co-expressing CXCR3, CCR4, CCR6 and CCR10 were studied in pSS patients and healthy controls. ...Chemotaxis assays were performed to study migration induced by CXCL10 and CCL25. Higher expression of CXCR3, CCR4 and …
Frequencies of circulating CCR9 + and CCR9- Th cells co-expressing CXCR3, CCR4, CCR6 and CCR10 were studied in pSS patients and healt …
Chemokines and Chemokine Receptors as Therapeutic Targets in Inflammatory Bowel Disease; Pitfalls and Promise.
Trivedi PJ, Adams DH. Trivedi PJ, et al. J Crohns Colitis. 2018 Aug 22;12(suppl_2):S641-S652. doi: 10.1093/ecco-jcc/jjx145. J Crohns Colitis. 2018. PMID: 30137309 Free PMC article. Review.
The principal targets for anti-chemokine therapy in inflammatory bowel disease (IBD) have been the receptors CCR9 and CXCR3 and their respective ligands CCL25 and CXCL10. More recently CCR6 and its ligand CCL20 have also received attention, the expression of the lat …
The principal targets for anti-chemokine therapy in inflammatory bowel disease (IBD) have been the receptors CCR9 and CXCR3 and their respec …
Chemokines in lymphocyte trafficking and intestinal immunity.
Kunkel EJ, Campbell DJ, Butcher EC. Kunkel EJ, et al. Microcirculation. 2003 Jun;10(3-4):313-23. doi: 10.1038/sj.mn.7800196. Microcirculation. 2003. PMID: 12851648 Review.
Several chemokines have been identified that are expressed in the GALT and/or the intestines themselves (TECK/CCL25, MEC/CCL28, and MIP-3alpha/CCL20) and play a role in intestinal lymphocyte localization, including unification of intestinal and other mucosa-associated effe …
Several chemokines have been identified that are expressed in the GALT and/or the intestines themselves (TECK/CCL25, MEC/CCL28, and M …
Chemokines as novel therapeutic targets for inflammatory bowel disease.
Nishimura M, Kuboi Y, Muramoto K, Kawano T, Imai T. Nishimura M, et al. Ann N Y Acad Sci. 2009 Sep;1173:350-6. doi: 10.1111/j.1749-6632.2009.04738.x. Ann N Y Acad Sci. 2009. PMID: 19758172 Review.
In this review, we will discuss the homeostatic and inflammatory roles of the chemokines and their receptors with their potentials and promise as molecular targets for therapeutic interventions in human IBD, focusing on the recently identified role of the CX3CL1-CX3CR1 axis, as w …
In this review, we will discuss the homeostatic and inflammatory roles of the chemokines and their receptors with their potentials and promi …
Evidence for PI-3K-dependent migration of Th17-polarized cells in response to CCR2 and CCR6 agonists.
Webb A, Johnson A, Fortunato M, Platt A, Crabbe T, Christie MI, Watt GF, Ward SG, Jopling LA. Webb A, et al. J Leukoc Biol. 2008 Oct;84(4):1202-12. doi: 10.1189/jlb.0408234. Epub 2008 Jun 27. J Leukoc Biol. 2008. PMID: 18586982
The respective chemokine agonists for CCR2 (CCL2 and CCL12), CCR6 (CCL20), and CCR9 (CCL25) elicited migration and PI-3K-dependent signaling events in Th17-polarized cells, thus indicating that all three receptors were functionally and biochemically responsive. ...P …
The respective chemokine agonists for CCR2 (CCL2 and CCL12), CCR6 (CCL20), and CCR9 (CCL25) elicited migration and PI-3K-depen …
CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4.
Matti C, D'Uonnolo G, Artinger M, Melgrati S, Salnikov A, Thelen S, Purvanov V, Strobel TD, Spannagel L, Thelen M, Legler DF. Matti C, et al. J Leukoc Biol. 2020 Jun;107(6):1137-1154. doi: 10.1002/JLB.2MA0420-295RRR. J Leukoc Biol. 2020. PMID: 32533638
Similarly, mouse CCL19, CCL21, and CCL25 equally activate the human receptor. Interestingly, at the same chemokine concentration, mouse CCL20 did not recruit beta-arrestins to human ACKR4. ...Furthermore, we engineered a fluorescently labeled chimeric chemokine consisting …
Similarly, mouse CCL19, CCL21, and CCL25 equally activate the human receptor. Interestingly, at the same chemokine concentration, mou …
Hypoxia Alters the Expression of CC Chemokines and CC Chemokine Receptors in a Tumor-A Literature Review.
Korbecki J, Kojder K, Barczak K, Simińska D, Gutowska I, Chlubek D, Baranowska-Bosiacka I. Korbecki J, et al. Int J Mol Sci. 2020 Aug 6;21(16):5647. doi: 10.3390/ijms21165647. Int J Mol Sci. 2020. PMID: 32781743 Free PMC article. Review.
Then we describe the effect of hypoxia on the expression of chemokines with the CC motif: CCL1, CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL15, CCL16, CCL17, CCL18, CCL19, CCL20, CCL21, CCL22, CCL24, CCL25, CCL26, CCL27, CCL28 together with CC chemokine receptors: …
Then we describe the effect of hypoxia on the expression of chemokines with the CC motif: CCL1, CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, CCL11, C …
CCL25 induces alpha4beta7 integrin-dependent migration of IL-17+ gammadelta T lymphocytes during an allergic reaction.
Costa MF, Bornstein VU, Candéa AL, Henriques-Pons A, Henriques MG, Penido C. Costa MF, et al. Eur J Immunol. 2012 May;42(5):1250-60. doi: 10.1002/eji.201142021. Eur J Immunol. 2012. PMID: 22539297 Free article.
CCL25 attracted CCR6(+) gammadelta T cells producing IL-17 (but not IFN-gamma or IL-4). OVA challenge triggered increased production of CCL25 followed by the accumulation of CCR9(+) , alpha(4) beta(7) (+) , and CCR6(+) /IL-17(+) gammadelta T cells into …
CCL25 attracted CCR6(+) gammadelta T cells producing IL-17 (but not IFN-gamma or IL-4). OVA challenge triggered increased prod …
24 results